New Dimensions to Hemodynamic Patient Monitoring

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Technology

Our Hemodynamic-Peripheral Flow Patient Monitoring system uses a compact and versatile optical sensor to deliver superior physiological parameter measurement capabilities. Based on miniaturized dynamic light scattering (mDLS) technology and advanced algorithms for multi-parametric detection, our truly non-invasive solution offers continuous monitoring during surgery, recovery, and other critical care conditions such as low perfusion, shock/sepsis, and bleeding. The sensor readings are resistant to ambient light and not affected by skin pigmentation. Contrary to the PPG sensor that measures blood volume fluctuations, our proprietary solution measures blood flow and other hemodynamic parameters, opening the door to endless opportunities for new applications.

Unique Sensor

Our compact and non-invasive sensor is based on Miniaturized Dynamic Light Scattering (mDLS) technology and proprietary signal processing algorithms. The versatile sensor can be placed anywhere on the body and can effectively measure a range of cardiovascular and physiological parameters. This flexibility allows for numerous app integration possibilities, from wearable patches to implantable neuromodulation devices. The sensor is resistant to the most challenging ambient light conditions and is not affected by any skin pigmentations.

Elfi-Tech’s sensing technology is not yet FDA cleared for commercial use. Expected US launch by 2024.

Use Cases

Artboard 1 P r ocess A u t omation Our p r ocess and Industrial A u t omation personnel a r e t r ained t o of f er a b r oad scope of se r vices t o meet or e x ceed y our p r oject goals. BLOOD CIRCULATION AND WOUND HEALING Non-invasive blood circulation monitoring can assist in wound healing SEPSIS Peripheral blood flow monitoring can detect decreased perfusion in the peripheral tissues, which is an indication of sepsis. HEMODYNAMIC STABILITY Cost Hemodynamic monitoring is commonly in intensive care units (ICUs) to assess the disease progression of critically ill patients and to adjust their treatment plans accordingly. PERHIPHERAL ARTERY DISEASE Non-invasive peripheral blood flow monitoring is a safe and effective way to assess the severity of peripheral artery disease (PAD) and monitor the response to treatment PERIPHERAL FLOW MONITORING Continuous peripheral flow monitoring enables early detection of critical changes in physiological conditions, which can allow for early intervention and improved outcomes. FLUID MANAGEMENT Peripheral hemodynamic monitoring can help clinicians optimize fluid management in patient care, particularly in critically ill or hospitalized patients. Learn more

Reduced Healthcare Costs

Reduced healthcare costs associated with peripheral blood flow monitoring are linked to shorter hospital stays, minimized intensive care resources, fewer diagnostic tests such as imaging studies and laboratory tests, reduced need for treatments such as mechanical ventilation and vasoactive medications, avoidance of secondary complications such as organ failure and fewer hospital readmissions.

Guiding Rehabilitation Programs

Especially after surgeries or injuries that impact circulation, monitoring blood flow during exercise or therapy sessions can help optimize rehabilitation programs, ensuring that the interventions are tailored to the individual's needs and maximizing the effectiveness of treatment.

Reduced Costs of Procedures

Identifying patients who are at high risk for complications from procedures. Early detection of reduced blood flow can assist in treatment modifications in a timely manner rather than in emergency or critical conditions.

Personalized Treatment Planning

Providing clinicians with objective data on an individual's circulatory health, to optimize medication management, lifestyle modifications, and interventions, resulting in better outcomes, reduced complications, and overall healthcare cost savings.

Reduced Hospital Stays

Providing a full picture of the patient status could allow for patients to be discharged from the hospital sooner. Form-factors with the integrated mDLS sensor enable exciting new home monitoring applications.

Preventing Complications

Early detection of critical ischemic episodes or worsening circulatory conditions can help prevent complications such as non-healing wounds, ulcers, infections and even limb amputation.

Reduced Readmission Rates

Identifying patients who are at risk for readmission and providing them with the appropriate interventions. Prior to releasing a patient, health care providers can more accurately evaluate the patient status and level of risk for deterioration.

Machine Learning

Machine learning can create predictive models that can forecast a patient’s hemodynamic status, such as the risk of developing sepsis or shock, based on their vital signs, lab results, and other data.  Machine learning can also analyze real-time hemodynamic data and alert healthcare providers of any abnormal changes, such as a sudden drop in blood pressure. These alarms can be managed to alert healthcare providers only when necessary, which can reduce alarm fatigue and improve patient care. Machine learning can also automatically diagnose hemodynamic conditions based on vital signs and other data, such as sepsis or hypovolemic shock, which can help to identify patients at risk of developing complications. These algorithms can be used to create personalized treatment plans based on a patient’s hemodynamic status and other factors, and can identify patterns in the data that are not obvious to the human eye, which can help to identify patients at risk of developing complications and to adjust therapy accordingly.

Testimonials

Professor Irwin Reiss

Head of Neonatology

ERASMUS MC

‘Elfi-Tech’s blood flow sensor has the potential to add a new dimension to our understanding of patient conditions in more detail’

Professor Albert Dahan

Head of the Anesthesia & Pain Research Unit

Leiden University Medical Center

‘By monitoring peripheral blood flow, we gain vital seconds or even minutes of warning prior to critical patient events’

Publications and Patents

US7758505
US8277384B2
EP2637559B1
US20190298186A1
US20090082642
US20090082642A1
US20180153420A1
US20220183579A1
US11134901
US8708907B2
WO2018069931A1
US20180160913A1
US20120130215A1
US10720755B2
US20150141766A1
US20210093204A1
WO2016185244A1

Strong INTELLECTUAL
PROPERTY

  • PROPRIETARY ALGORITHMS AND KNOW-HOW
  • 16 PATENT APPLICATIONS IN 5 PATENT FAMILIES
  • Covering the technology and applications
  • 13 granted with coverage in the US, EU and Japan

Clinically Proven Technology

  • 8 publications in peer reviewed journals
  • 9 conference papers and posters
  • 406 citations
  • 12 Clinical trial sites in the US, EU and Israel covering multiple mDLS applications

Links to Publications

Contact us at info@elfi-tech.com

Elfi-Tech’s mission is to develop non-invasive blood flow monitoring solutions for in-hospital and home care. 

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Free Sensor

The free sensor form factor can be applied anywhere on the body with a custom adhesive sticker. Monitoring of peripheral blood flow and associated parameters can be done from anywhere on the body during a procedure or long term patient monitoring.

Finger Cuff

Elfi-Tech’s finger cuff enables occlusion on the finger root in order to enable measurement of absolute blood pressure continuously. Simultaneously, the same mDLS sensor monitors peripheral blood flow and all associated parameters.

Finger Clip

As a known form factor in the patient monitoring world, the mDLS sensor can easily be integrated into a pulse oximeter in order to add a new dimension of cardiovascular parameters.

USE CASES

Blood Circulation and wound healing

Non-invasive blood circulation monitoring can assist in wound healing by:

  • Identifying patients who are at risk for delayed wound healing: It can be used to measure blood flow to the affected area. If blood flow is decreased, it can slow down the healing process. By identifying patients who are at risk for delayed wound healing, it can help to ensure that they receive the appropriate treatment.
  • Monitoring the healing process: It can be used to track the healing process over time. This information can help the doctor determine if the wound is healing properly and if any changes need to be made to the treatment plan.
  • Evaluating the effectiveness of treatment: It can be used to evaluate the effectiveness of treatment. If blood flow to the affected area increases after treatment, it is a sign that the treatment is working and that the wound is healing properly.

Overall, blood circulation monitoring is a valuable tool that can help to improve the healing process for patients with wounds.

  • In patients with diabetes, blood circulation monitoring can be used to identify those who are at risk for foot ulcers. Foot ulcers are a common complication of diabetes and can lead to amputation. Blood circulation monitoring can be used to monitor blood flow to the feet and identify those who are at risk for developing foot ulcers. These patients can then be given preventive treatment, such as proper footwear and foot care, to help prevent foot ulcers from developing.
  • In patients with peripheral artery disease (PAD), blood circulation monitoring can be used to identify those who are at risk for delayed wound healing. PAD is a condition that occurs when the arteries that carry blood to the limbs become narrowed or blocked. This can reduce blood flow to the limbs, which can slow down the healing process. NIBM can be used to identify patients with PAD and give them the appropriate treatment, such as medication or surgery, to improve blood flow to the limbs and help wounds heal faster.
  • In patients with pressure ulcers, blood circulation monitoring can be used to monitor the healing process and evaluate the effectiveness of treatment. Pressure ulcers are sores that develop on the skin due to pressure, friction, or shearing forces. Blood circulation monitoring can be used to measure blood flow to the area of the pressure ulcer and track the healing process over time. This information can help the doctor determine if the wound is healing properly and if any changes need to be made to the treatment plan.
USE CASES

FLUID MANAGEMENT

Peripheral hemodynamic monitoring can help clinicians optimize fluid management in patient care, particularly in critically ill or hospitalized patients. It can provide information about the patient’s cardiovascular status, including their cardiac output and peripheral vascular resistance; detect changes in peripheral perfusion, such as decreased blood flow to the extremities; and help identify patients who are at risk of developing complications related to poor peripheral perfusion, such as pressure ulcers or peripheral neuropathy. By identifying these patients early, clinicians can adjust fluid and medication therapies accordingly to maintain optimal cardiovascular function, prevent complications, and improve patient outcomes.

USE CASES

SEPSIS

Peripheral blood flow monitoring can detect decreased perfusion in the peripheral tissues, which is an indication of sepsis. Other indicators of sepsis that can be detected through peripheral blood flow monitoring include microcirculation, such as capillary leak and vasodilation and assessing the patient’s response to therapy, such as fluid therapy or vasopressor therapy.
USE CASES

HEMODYNAMIC STABILITY

Hemodynamic monitoring is commonly used in intensive care units (ICUs) to assess the disease progression of critically ill patients and to adjust their treatment plans accordingly. It helps clinicians determine the effectiveness of treatments such as fluid administration, vasopressors, and inotropes in maintaining the patient’s hemodynamic stability. Hemodynamic monitoring is critical during cardiac surgery to ensure that the patient’s cardiovascular system is functioning correctly and to detect any complications that may arise during or after the procedure. This level of monitoring is also used for patients undergoing anesthesia, patients with chronic cardiovascular conditions, and in the emergency department to help diagnose and manage conditions such as sepsis, shock, and heart failure. Hemodynamic monitoring is also used in clinical research to study the pathophysiology of cardiovascular disease, assess the efficacy of new treatments, and improve patient outcomes.
USE CASES

PERIPHERAL FLOW MONITORING

Continuous peripheral flow monitoring enables early detection of critical changes in physiological conditions, which can allow for early intervention and improved outcomes. The mDlS technology can provide important information about the patient’s condition that is not available with traditional hemodynamic monitoring methods. Peripheral microcirculation assessment is essential for monitoring the progression of chronic conditions such as peripheral artery disease, diabetes, and hypertension; for post-operative care, such as patients who have undergone revascularization procedures; and for monitoring wound healing such as diabetic foot ulcers or pressure ulcers. Other areas where peripheral blood flow assessment is necessary are in geriatric patients at risk of developing age-related conditions such as frailty; pediatric patients at risk of developing complications such as acute kidney injury; and in sports medicine for those at risk of developing exercise-induced injuries or conditions.

USE CASES

Perhipheral Artery Disease

Non-invasive peripheral blood flow monitoring is a safe and effective way to assess the severity of peripheral artery disease (PAD) and monitor the response to treatment. Peripheral flow monitoring can be used before, during, and after a vascular intervention procedure to help ensure patient safety and optimize outcomes.

  • Peripheral flow monitoring can be used to assess the severity of PAD before a vascular intervention procedure. This information can help the doctor determine the best course of treatment and the risks and benefits of the procedure. For example, if a patient has severe PAD, they may be at increased risk for complications during surgery.
  • Peripheral flow monitoring can be used to identify patients who are at risk for developing blood clots after a vascular intervention procedure. This information can help the doctor prescribe the appropriate medications to prevent blood clots.

Benefits of Peripheral flow monitoring during an angioplasty procedure:

  • Peripheral flow monitoring can be used to monitor the patient’s blood flow during the vascular intervention procedure. This information can help the doctor identify any problems with blood flow and take steps to correct them. For example, if a patient’s blood flow decreases during the procedure, the doctor may need to adjust the procedure or use a different technique.
  • Peripheral flow monitoring can be used to monitor the patient’s pain during the vascular intervention procedure. This information can help the doctor ensure that the patient is comfortable and that they are not experiencing any pain.

Benefits of Peripheral flow monitoring after a vascular intervention procedure:

  • Peripheral flow monitoring can be used to monitor the patient’s blood flow after a vascular intervention procedure. This information can help the doctor identify any problems with blood flow and take steps to prevent complications. For example, if a patient’s blood flow decreases after surgery, the doctor may need to prescribe medication or recommend physical therapy.
  • Peripheral flow monitoring can be used to monitor the patient’s pain after a vascular intervention procedure. This information can help the doctor ensure that the patient is comfortable and that they are not experiencing any pain.

Peripheral flow monitoring is a valuable tool for monitoring patients with PAD before, during, and after a vascular intervention procedure. It can help to ensure patient safety and optimize outcomes.